Structural Biology

11 results.

March 24, 2024 Tuberculosis is an ancient problem. Modern technology is helping solve it

Van Andel Institute’s Dr. Huilin Li is using modern technology to solve an ancient problem that still has devastating consequences today: tuberculosis (TB), a…

August 1, 2022 Five years of fueling discovery with cryo-EM

To understand life’s building blocks — the molecules that give structure to our cells, fuel our bodies and play integral roles in health and disease…

March 21, 2022 Cryo-EM reveals how ‘911’ molecule helps fix damaged DNA

GRAND RAPIDS, Mich. (March 21, 2022) — When something goes wrong during DNA replication, cells call their own version of 911 to pause the process…

June 24, 2021 A ‘tasty’ protein may lead to new ways to treat metabolic and immune diseases

GRAND RAPIDS, Mich. (June 24, 2021) — The same taste-sensing molecule that helps you enjoy a meal from your favorite restaurant may one day lead…

June 3, 2020 Near-atomic blueprint reveals inner workings of drug target for cancer, other diseases

GRAND RAPIDS, Mich. (June 3, 2020) — Van Andel Institute scientists have for the first time described the near-atomic level structure of a molecular pathway…

October 3, 2018 High-resolution “blueprint” reveals mechanism that helps E. coli infect the urinary tract

GRAND RAPIDS, Michigan (October 3, 2018) — A common gut bacterium uses a unique assembly apparatus to build hair-like structures that help it infect the…

September 24, 2018 Cryo-EM reveals structure of protein responsible for regulating temperature in the human body

GRAND RAPIDS, Mich. (September 24, 2018) — A team led by Van Andel Research Institute (VARI) scientists has revealed for the first time the…

January 22, 2018 Cryo-EM reveals critical protein-modifying complex and potential drug target

GRAND RAPIDS, Mich. (Jan. 22, 2018)—Scientists have revealed the atomic-level structure of a molecular complex responsible for modifying proteins, possibly paving the way for the…