Research

8 results.

March 24, 2024 Tuberculosis is an ancient problem. Modern technology is helping solve it

Van Andel Institute’s Dr. Huilin Li is using modern technology to solve an ancient problem that still has devastating consequences today: tuberculosis (TB), a…

August 1, 2022 Five years of fueling discovery with cryo-EM

To understand life’s building blocks — the molecules that give structure to our cells, fuel our bodies and play integral roles in health and disease…

March 21, 2022 Cryo-EM reveals how ‘911’ molecule helps fix damaged DNA

GRAND RAPIDS, Mich. (March 21, 2022) — When something goes wrong during DNA replication, cells call their own version of 911 to pause the process…

June 24, 2021 A ‘tasty’ protein may lead to new ways to treat metabolic and immune diseases

GRAND RAPIDS, Mich. (June 24, 2021) — The same taste-sensing molecule that helps you enjoy a meal from your favorite restaurant may one day lead…

October 3, 2018 High-resolution “blueprint” reveals mechanism that helps E. coli infect the urinary tract

GRAND RAPIDS, Michigan (October 3, 2018) — A common gut bacterium uses a unique assembly apparatus to build hair-like structures that help it infect the…

September 24, 2018 Cryo-EM reveals structure of protein responsible for regulating temperature in the human body

GRAND RAPIDS, Mich. (September 24, 2018) — A team led by Van Andel Research Institute (VARI) scientists has revealed for the first time the…

June 13, 2018 Cryo-EM reveals interaction between major drug targets

GRAND RAPIDS, Mich. (June 13, 2018) — For the first time, scientists have visualized the interaction between two critical components of the body’s vast cellular…

February 21, 2017 ORC as Loader of the Rings: Study details ringed structure of ORC in DNA replication

GRAND RAPIDS, Mich. (Feb. 21, 2017)—An international collaboration of life scientists, including experts at Van Andel Research Institute, has described in exquisite detail the…